However, I routinely use PTGui Pro to output a separate panorama for each of the exposure levels and then send them to TuFuse Pro for exposure fusion into a final panorama which can then fee tweaked in Photoshop. As Richard says it is capable of both exposure fusion and focus stacking, either alone or simultaneously. Through Autopano you can generate a spherical panorama in JPG, PNG, TIFF, PSD / PSB, HDR, EXR and KRO, in 8 bit, 16 bit or 32 bit, all dependent upon the format you wish to use. I have used TuFuse Pro for years, although less so in recent years. Key Details of Autopano Video (64-bit) Stitch and create 360-degree immersive videos automatically. Tufuse the commandline utility is I think free, but Tufuse Pro is a paid (cheap) product. but there's a package called 'Tufuse Pro' which offers a Gui for focus stacking among other kinds of image combine via Fusion methods. However, IIRC, enfuse doesn't have a GUI for focus stacking, last time I did it on the CLI a few years back, maybe there's an easier way now?

I would focus stack individual frame first. Thanks, so for panos I would use Hugin first but, If I am doing focus stacking with the same images as for pano, would I need to first do the stacking in Enblend or Enfuse?

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